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Updated: 9 hours 41 min ago

Cochrane seeks Synthesis Methodology Editor

Wed, 02/09/2022 - 16:34

Cochrane’s Methods Support Unit was established in 2019 to provide methodological support in the production of high quality, high priority Cochrane systematic reviews.

The Methods Support Unit provides guidance and hands on statistical and methods support to Cochrane systematic reviews, including those using complex methods or non-randomised study designs. The unit comprises two part time Statistical Editors and one full time Evidence Synthesis Methodology Editor.  

As Evidence Synthesis Methodology Editor, you will provide methodological support and general systematic review methods advice for reviews in process, field queries from the Community Support Team, and provide methods peer review as requested. You may also be required to provide subject matter expertise for the development of specific features in tools and software used in the production of Cochrane Reviews.

The role will require a very good understanding of methods such as the assessment of risk of bias for different study designs, application of GRADE and interpretation of findings in the review. An understanding of statistical meta-analysis methods is advantageous in the role, although specialist statistical editors in the unit will be able to provide this advice.

The majority of Cochrane Central Executive staff are located in London, UK, however flexible location or a part-time appointment are possible for the right candidate.

How to apply

  • For further information on the role and how to apply, please click here.  
  • The deadline to receive your application is by Friday 25 February.  
  • The supporting statement should indicate why you are applying for the post, and how far you meet the requirements, using specific examples.
  • Note that we will assess applications as they are received, and therefore may fill the post before the deadline.
Wednesday, February 9, 2022 Category: Jobs

Trusted information needs to be protected on social media as much as misinformation needs to be challenged

Tue, 02/08/2022 - 17:01

Recent removal of Cochrane’s Instagram post and shadowban highlight the realities of Cochrane’s call against misinformation

Cochrane’s health evidence syntheses are recognised as the international gold standard for high quality, trusted information. Our reviews are used to support global and national health guidelines and policy. We advocate for evidence-informed healthcare and make our trusted evidence accessible and available to all. One way we do this is using social media to reach different audiences. 

In recent days, Cochrane has again been the subject of an Instagram misinformation blunder, with a post about a Cochrane Review on Ivermectin for prevention and treatment of COVID-19 being removed from the platform. Also Cochrane’s Instagram account has been denied the verification blue check mark several times. We are aware that other research publishers, such as the BMJ, have also experienced similar issues.

The first time this happened in November, Cochrane’s Instagram account was ‘shadowbanned’ for a few weeks; people could not tag or mention @cochraneorg on the platform. While little specifics were given, there was a notification that the account ‘repeatedly posted content that goes against Community Guidelines on false content about COVID-19 or vaccines.’ This shadowban happened just days after Cochrane helped lead a campaign to tackle misinformation for World Evidence-Based Healthcare Day and launched a course with Lifeology about identifying and preventing infodemics.

“The removal of our Cochrane post on Instagram comes just days before the launch of the Cochrane Convenes Report which calls for generating trust in evidence and countering mis/disinformation.” says Cochrane’s Editor in Chief, Dr Karla Soares-Weiser.

Drawing on experiences of the COVID-19 pandemic, Cochrane Convenes brought together leaders in health research and health evidence to explore and recommend the changes needed in evidence synthesis to prepare for and respond to future global health emergencies. The full report of the recommendations is being released 16 February.

“It’s not clear if there is an issue with Instagram’s algorithm or if the issue lies with people ‘gaming’ policies and reporting posts as misinformation when they are not. What is clear is that there is an issue with how you hold those deliberately creating and sharing mis/disinformation to account and how you form accreditation and approval for official sources of evidence that have met certain quality control standards. We need to make it easier for people to access trustworthy information – and that includes on social media.”

Cochrane is a proud supporter of WHO’s call to action on infodemic management and is currently collaborating with science communicators at Lifeology and the Association for Healthcare Social Media  and welcomes the opportunity to work directly with social media platforms and with others interested in tackling misinformation.

 

Tuesday, February 8, 2022

Cochrane seeks Systems & Product Development Editor

Tue, 02/08/2022 - 09:05

Location: Flexible location (remote working) in the UK.
Specifications: Permanent contract.
Hours: Full-time week 37.5 hours.
Salary: £52,000 per annum.
Application Closing Date: Sunday 27 February (Midnight GMT Time)

The Systems and Product Development Editor will provide strategic editorial and methods leadership to other departments to ensure editorial and methods strategy is reflected in Cochrane’s products, processes and technology.

The key purpose of the role is to deliver cross-departmental strategic objectives and targets by:

  1. Working closely with the Head of Change Management and Deputy Editor in Chief to help develop and deliver technological elements of Cochrane’s strategy for review production
  2. Providing editorial and methods oversight to align review production developments with Cochrane’s product development strategy
  3. Providing editorial and methods oversight to develop Cochrane’s review production systems and processes to deliver the review production strategy
  4. Engaging with members of the Cochrane community to help develop new products, systems and tools

Cochrane is a global, independent network of health practitioners, researchers, patient advocates and others, responding to the challenge of making vast amounts of research evidence useful for informing decisions about health. We do this by synthesizing research findings to produce the best available evidence on what can work, what might harm and where more research is needed. Our work is recognised as the international gold standard for high quality, trusted information.

  • For further information on the job description and how to apply, please click here. 
  • The supporting statement should indicate why you are applying for the post, and how far you meet the requirements, using specific examples. Note that we will assess applications as they are received, and therefore may fill the post before the deadline.
  • Deadline for applications: Sunday 27 February 2022 (Midnight GMT).
  • Interviews to be held on: W/C 7 March 2022 (times and exact dates to be confirmed).
Tuesday, February 8, 2022 Category: Jobs

Cochrane seeks Managing Editor

Mon, 02/07/2022 - 16:09

Specifications: Full Time (Fixed Term/Consultancy role)
Salary: circa £40,000 per annum
Location: Flexible
Application Closing Date:  Friday 25 February 2022

Cochrane has established a centrally-resourced Editorial Service to support the efficient and timely publication of high-quality systematic reviews in the Cochrane Library. The reviews that are published through the Central Editorial Service address some of the research questions considered to be the most important to decision makers.

The Central Editorial Service is also running a pilot of approaches to increase editorial efficiency and integrity within Cochrane. The Managing Editor role will play a key role in operationalising this pilot.

Reporting to the Executive Editor of the Central Editorial Service, the Managing Editor will manage the editorial process of protocols and reviews submitted to the Central Editorial Service. The role-holder should be alert to the demands of delivering high-quality review content for publication in a timely fashion, and work to ensure that deadlines can be met.   

Cochrane is a global, independent network of health practitioners, researchers, patient advocates and others, responding to the challenge of making vast amounts of research evidence useful for informing decisions about health. We do this by synthesizing research findings to produce the best available evidence on what can work, what might harm and where more research is needed. Our work is recognised as the international gold standard for high quality, trusted information. An understanding of Cochrane’s work and health research more generally is an advantage, but not essential.

The majority of Cochrane Central Executive staff are located in London, UK, however flexible location or a part-time appointment are possible for the right candidate.

How to apply

  • For further information on the role and how to apply, please click here
  • The deadline to receive your application is by Friday 25 February. 
  • The supporting statement should indicate why you are applying for the post, and how far you meet the requirements, using specific examples. Note that we will assess applications as they are received, and therefore may fill the post before the deadline.
  • Interviews to be held on: week commencing 7 March 2022.
Monday, February 7, 2022 Category: Jobs

Cochrane's 2022 International Women’s Day Events

Wed, 02/02/2022 - 19:38

In recognition of International Women’s’ Day (IWD) happening March 8th, Cochrane will be hosting several events and activities. The IWD 2022 theme is “breaking gender bias and reducing stereotypes and discrimination to promote diversity, equity, and inclusion.”

The Annual Anne Anderson Walk is a cherished annual social event in Cochrane, where attendees walk to celebrate women's contributions to Cochrane while raising money to annual Anne Anderson Award.  Everyone is welcome to snap a picture of themselves and share their walk with the Community. Pictures will be posted on social media and the website as we encourage each other to get out on a walk - everyone is welcome to join in! 

Calling all science communicators and artists! Cochrane will be hosting an exciting challenge in collaboration with Lifeology. We would like to see your art and graphics that illustrate the IWD theme in relation to healthcare and/or evidence synthesis. 

Top submissions will be promoted on Cochrane social media pages and platforms, and the winner will be announced as part of the Cochrane US Women’s Day Panel and with an interview news item on Cochrane.org.  The winning graphic will also be used for a tote bag and mug, with credit to the creator, and will be available for purchase in the Cochrane Store.

Submission criteria:

  • Graphic should resonates with evidence synthesis / health science and this year’s IWD theme.  
  • .png file type preferred, full colour
  • Follow @Cochrane_US on Twitter 
  • Email submission to tduque@cochrane.org with subject “IWD Graphic Submission”
  • Accepted now through March 1st, 2022

 

Join Cochrane US and Agency for Healthcare Research and Quality (AHRQ) for an enlightening and informative panel to highlight gender bias in health science and evidence synthesis. The panel will talk about their career, history, motivations, and encounters with gender bias.

Stay tuned for more information on the panel and how to register!

Tuesday, January 18, 2022

Cochrane Skin seeks 2 Systematic Reviewers - Nottingham, UK

Wed, 02/02/2022 - 16:32

Specifications: Fixed term post until 31 March 2023. Part or full-time. 
Location: Nottingham, UK
Salary: £27924 to £40927 per annum
Application deadline:
16 Feb 2022

A new opportunity has arisen for two Systematic Reviewers to join the Cochrane Skin team at its editorial base within the Centre of Evidence Based Dermatology (CEBD), School of Medicine, University of Nottingham. CEBD has an international reputation for research into the prevention and treatment of skin disease with a focus on delivering independent clinical research that informs the NHS.

Cochrane Skin is part of the international Cochrane organisation, and is the editorial base for the preparation and dissemination of Cochrane systematic reviews on the treatment and prevention of skin diseases. It is one of 62 Cochrane review groups worldwide which contribute to Cochrane, and this busy editorial base currently has around 20 review teams preparing protocols or reviews for publication or updating published reviews. In working as a Systematic Reviewer, you will lead and support systematic reviews within the Cochrane Skin portfolio in order to ensure the delivery of high-quality, timely evidence synthesis to support healthcare decision-making. You will be responsible for working with review teams to support title screening, data extraction, risk of bias assessment and contributing to the write-up of Cochrane Skin systematic reviews, and will ensure that your work adheres to relevant methodological guidance. 

They are seeking an individual with proven knowledge and experience of involvement in systematic reviews e.g. by participating as an author in a Cochrane systematic review or conducting a systematic review as a lead author. You should possess a good understanding of systematic review procedures, including knowledge of risk of bias assessment with an ability to critically appraise clinical trials. Excellent verbal and written communication skills, organisational skills and the ability to evaluate published clinical trial manuscripts are also essential. They particularly welcome applications from candidates with knowledge of Cochrane risk of bias 2.0 methodology.

Wednesday, February 2, 2022 Category: Jobs

Cochrane seeks Software Test Engineer

Wed, 02/02/2022 - 15:36

Specifications: Permanent, Full time
Salary:
circa £55,000 per annum
Location:
Copenhagen
Application deadline:
14 February 2022

Are you passionate about quality software? Do you have a drive to make a difference for health care world-wide?
We are a global, independent organization that strives to inform health-care decisions every day. We gather and summarize the best evidence from research to help doctors, nurses, patients, carers, researchers, funders, and policymakers. We do not accept commercial or conflicted funding, and work to minimize risk of bias, in order to generate authoritative and reliable information.

Our development team is located in Copenhagen and supports the process of creating systematic reviews through a web-based application. We are a group of motivated, mission-driven people who are energized by working together. We care about our users, taking pride in delivering features which both ensure the quality of Cochrane systematic reviews and make review production easier and more efficient.

As our software test engineer, you'd be leading the testing of our software, as well as helping us upgrade and build automated tests for our product. Our goal is to maintain product development velocity while having confidence in the quality of our code.

Who we’re after
We are primarily looking for someone motivated by the mission of Cochrane and of our development team – that is, someone who cares about facilitating improved evidence-based healthcare decisions. We would consider it a bonus if you have specific knowledge of Cochrane, evidence-based health care, systematic reviews, and/or the global health sector.

On a technical level, we are looking for an analytical and efficient problem solver that can challenge our product and the processes around it, with experience in designing and implementing test strategies for web applications in an Agile setting.

We work in English.

What you'd be doing

  • Working with a talented, passionate and collaborative agile team;
  • Advocating cross-team to ensure quality-minded practices;
  • Designing, implementing, and maintaining automatic and manual test solutions.

How to apply

  • For further information on the role and how to apply, please click here. 
  • The deadline to receive your application is by 14 February 2022. 
  • The supporting statement should indicate why you are applying for the post, and how far you meet the requirements, using specific examples. Note that we will assess applications as they are received, and therefore may fill the post before the deadline.
Wednesday, February 2, 2022 Category: Jobs

Cochrane seeks Software Developer

Wed, 02/02/2022 - 15:26

Location: Copenhagen, Denmark
Specifications:
Permanent contract
Hours:
Full-time week (flexible working considered) – 37.5 hours
Salary:
£55,500 per annum
Application Closing Date:
14 February (Midnight GMT Time)

Are you passionate about quality software? Do you have a drive to make a difference for health care world-wide?
We are a global, independent organization that strives to inform health-care decisions every day. We gather and summarize the best evidence from research to help doctors, nurses, patients, carers, researchers, funders, and policymakers. We do not accept commercial or conflicted funding, and work to minimize risk of bias, in order to generate authoritative and reliable information.

Our development team is located in Copenhagen and supports the process of creating systematic reviews through a web-based application. We are a group of motivated, mission-driven people who are energized by working together. We care about our users, taking pride in delivering features which both ensure the quality of Cochrane systematic reviews and make review production easier and more efficient.

As our new software developer, you'd contribute to the design and development of the web-based software used by thousands of Cochrane authors to produce systematic reviews, which includes tools and integrations for writing, statistical analysis, data management, study curation, data extraction, and more. Due to the fast-paced nature of our release cycle, the team interact frequently with users and other stakeholders.

Who we’re after
We are primarily looking for someone motivated by the mission of Cochrane and of our development team – that is, someone who cares about facilitating improved evidence-based healthcare decisions. We would consider it a bonus if you have specific knowledge of Cochrane, evidence-based health care, systematic reviews, and/or the global health sector.

On a technical level, we are looking for an analytical and efficient problem solver that can challenge our product and the processes around it, with experience in designing and building web applications in an Agile setting.

We work in English.

What you'd be doing

  • Working with a talented, passionate and collaborative agile team;
  • Designing, developing, testing, and maintaining our review production systems;
  • Achieving and maintaining a high level of automated test coverage;
  • Helping to drive continuous improvement of product, code, and processes.

For further information on the job description and how to apply, please click here. 

  • The supporting statement should indicate why you are applying for the post, and how far you meet the requirements, using specific examples. Note that we will assess applications as they are received, and therefore may fill the post before the deadline.
  • Deadline for applications: 14 February 2022 (Midnight GMT).
  • Interviews to be held on: W/C 28 February 2022 (times and exact dates to be confirmed).
Wednesday, February 2, 2022 Category: Jobs

Interview with authors of Hip Fracture reviews

Mon, 01/31/2022 - 13:19

In this interview, we learn more about a series of reviews on hip fractures published on the Cochrane Library and talk to some of the authors behind this work Prof Xavier Griffin and orthopaedic surgeons Mr William Eardley and Mr Martyn Parker.

Tell us how did these reviews come about?
This work was funded by the National Institute of Health Research Systematic Reviews programme, as a joint application from Oxford University and Cochrane’s Bone, Joint and Muscle Trauma Group. The underlying concept was that there is diverse, congested and complex literature of varying quality around hip fracture and it can be hard to interpret. We wanted to improve on that and provide useful, actionable statements of the evidence for patients, clinicians and researchers.

Studies are being accumulated very quickly in this field compared to other areas of orthopaedics and the reviews that were in the Cochrane Library were out of date and had various limitations. We were aware that NICE would be reviewing and updating its guidance on the management of hip fracture in adults in 2022 so this was a timely piece of work that would link closely with work at NICE. We were in touch with them along the process sharing the questions for which patients and clinicians wanted answers, as well as sharing findings with them.

Were patients involved?
We carried out scoping work with patients and experts in this field to work out what the priority review topics would be - there could have been a hundred, but we worked together to reduce it down to what was most important. We shared this with NICE to help shape their update. This involvement of patients and their views was not happening when we all started out in this field, it is now so much more patient influenced, which is a good thing for those giving and those receiving treatment and care.



We approached these reviews as informative pieces of work giving direction to guidelines, clinical practice and research rather than being static sources of information - they feed into knowledge and then clinical practice.

Who will find these studies most useful?
Clinicians, surgeons, and trainee surgeons will find these reviews most useful as they provide the gold standard answers to questions they want answered.

The studies are also an important part of the puzzle in terms of informing what might be commissioned for research later.

We hope patients will see an improvement in their care as a result of these reviews as they give an evidence-based anchors for clinician’s recommendations.  NICE will also have these studies available to them when they update their guidance on this topic.

In the UK we have something called the National Hip Fracture Database, it audits treatment in this area, how many hip replacements take place in the UK for example. With these reviews they can report practice against best evidence which is good for patients, good for commissioners and good for people planning service delivery in their hospitals.

Who was involved?
Our success in securing this grant and the reviews done to date builds on very strong networks,
we've got a pretty research active and research savvy community partly through the work of Orthopaedic Trauma Society and the Fragility Fracture Network – we drew on this network to pull this work together. This research collaboration is what we’d like to see fostered going forwards.

These reviews were synchronised with current large trials and NICE updating their guidelines and as such they are an important piece of work to inform the wider picture and influence practice; not only in terms of influencing what treatment is given but influencing how best to study a topic – this is a shift in culture. These reviews should stand the test of time for the next ten years because they have been performed with methodological rigour and include the latest trial data.

You included very recent large landmark trials, how?
We did not want to publish Cochrane reviews that were out of date quickly. We were able to include a very large landmark new trial (WHITE5) in two of these reviews because we were aware of what each other was doing – we were in touch with each other - and we were able to access trial data prior to publication. We don’t work in a siloed way, and this has great benefit.

What value do these studies have for funders?
This body of work will help funders know where to place their funding to get maximum benefit on that spend – there are certain surgeries we can say should no longer happen and those areas no longer need to be studied.

Monday, February 14, 2022

Cochrane seeks Financial Accountant

Thu, 01/27/2022 - 16:17

Location: Flexible location (remote working) in the UK.
Specifications: Permanent contract.
Hours: Full-time week (flexible working considered) – 37.5 hours.
Salary: £42,000 per annum.
Application Closing Date: Sunday 20 February (Midnight GMT Time)

This role is an exciting opportunity to use your financial knowledge and problem-solving skills to make a difference in the field of health care research.  

The Financial Accountant is responsible for supporting the day-to-day management and the smooth running of the financial accounting operations of Cochrane, which includes leading on financial accounting processes, balance sheet reconciliations and supporting the international payroll.  The jobholder will have an important role to create and shape the financial procedures, improve processes, outputs, and analysis for stakeholders.

You will have a minimum of 3-5 years’ experience in a similar finance role with a recognised qualification. Part-qualified candidates with particularly strong experience will be considered and supported.

Cochrane is a global, independent network of health practitioners, researchers, patient advocates and others, responding to the challenge of making vast amounts of research evidence useful for informing decisions about health. We do this by synthesizing research findings to produce the best available evidence on what can work, what might harm and where more research is needed. Our work is recognised as the international gold standard for high quality, trusted information.

  • For further information on the job description and how to apply, please click here 
  • The supporting statement should indicate why you are applying for the post, and how far you meet the requirements, using specific examples. Note that we will assess applications as they are received, and therefore may fill the post before the deadline.
  • Deadline for applications: Sunday 20 February 2022 (Midnight GMT).
  • Interviews to be held on: W/C 28 February 2022 (times and exact dates to be confirmed).
Thursday, January 27, 2022 Category: Jobs

Featured review: Low-carbohydrate versus balanced-carbohydrate diets for reducing weight and cardiovascular risk

Tue, 01/25/2022 - 15:23

Low‐carbohydrate versus balanced‐carbohydrate diets for reducing weight and cardiovascular risk

Key messages

  • There is probably little to no difference in the weight lost by people following low-carbohydrate weight-reducing diets (also known as 'low-carb diets') compared to the weight lost by people following balanced-carbohydrate weight-reducing diets, for up to two years.
  • Similarly, there is probably little to no difference between the diets for changes in heart disease risks, like diastolic blood pressure, glycosylated haemoglobin (HbA1c, a measure of blood sugar levels over 2-3 months) and LDL cholesterol (‘unhealthy’ cholesterol) up to two years.
  • This was the case in people with and without type 2 diabetes.

What are low-carbohydrate and balanced-carbohydrate weight-reducing diets?
People spend lots of money on trying to lose weight using diets, products, foods and books, and continue to debate about which diets are effective and safe. So, examining the scientific evidence behind claims made is important. Low-carbohydrate diets are a broad category of weight-reducing diets that manipulate and restrict carbohydrates, protein and fat in diets. There are no consistent, widely-accepted definitions of these diets and different descriptions are used (e.g. 'low-carbohydrate, high-protein’, 'low-carbohydrate, high-fat', or ‘very low-carbohydrate’).

Low-carbohydrate diets are implemented in different ways, but they restrict grains, cereals and legumes, and other carbohydrate-containing foods; such as dairy, most fruit and certain vegetables. These foods are then typically replaced with foods higher in fat and protein; such as meats, eggs, cheese, butter, cream, oils. Some low-carbohydrate diets recommend eating as desired, while others recommend restricting the amount of energy eaten.

Balanced-carbohydrate diets contain more moderate amounts of carbohydrates, protein and fats, in line with current healthy eating advice from health authorities. When used for weight reduction, balanced diets recommend restricting the amount of energy eaten by guiding people to reduce their portion sizes and choose healthier foods (e.g. lean instead of fatty meat).

Low-carbohydrate weight-reducing diets are widely promoted, marketed and commercialised as being more effective for weight loss, and healthier, than 'balanced'-carbohydrate weight-reducing diets.


Professor Celeste Naude explains, "The weight lost by people on low-carbohydrate weight-reducing diets was similar to the weight lost by those on balanced-carbohydrate weight-reducing diets, for up to two years. Changes in heart disease risk factors were also similar in people following these diets for between one and two years. This was the case in people with and without type 2 diabetes.

"The longest of the trials lasted for two years, so we do not know if there are differences between the effects and safety of these diets beyond two years, which would be especially important for heart disease risk factors.

Most of the people in the trials did not have heart disease or related risks at the start of the studies, so we do not know if there are differences between the effects and safety of these diets in people with heart disease or risk factors, such as conditions that cause abnormal levels of fats in the blood.

Our review did not compare type or quality of carbohydrates, fats or proteins between the diets, or costs between the diets.”


What did the review authors want to find out?
They wanted to find out if low-carbohydrate weight-reducing diets were better for weight loss and heart disease risk factors than balanced-carbohydrate weight-reducing diets in adults who were overweight or living with obesity.

They wanted to find this out for people with and without type 2 diabetes.

What did they do?
They searched six electronic databases and trial registries for all trials* that compared low-carbohydrate weight-reducing diets with balanced-carbohydrate weight-reducing diets in adults who were overweight or living with obesity. The trials had to last for at least three months. The authors compared and summarised the results of the trials and rated the confidence in the combined evidence, based on factors such as study methods and sizes.

*A trial is a type of study in which participants are assigned randomly to two or more treatment groups. This is the best way to ensure similar groups of participants.

What did they find?
The authors found 61 trials involving 6925 people who were overweight or living with obesity. The biggest trial was in 419 people and the smallest was in 20 people. All except one of the trials were conducted in high-income countries worldwide, and nearly half were undertaken in the US (n=26).

Most trials were undertaken in people who did not have heart disease or risk factors (n = 36). Most people (n = 5118) did not have type 2 diabetes.

The average starting weight of people across the trials was 95 kg. Most studies lasted for six months or less (n = 37); and the longest studies (n = 6) lasted for two years.

Main results
Low-carbohydrate weight-reducing diets probably result in little to no difference in weight loss over the short term (trials lasting 3 to 8.5 months) and long term (trials lasting one to two years) compared to balanced-carbohydrate weight-reducing diets, in people with and without type 2 diabetes.

In the short term, the average difference in weight loss was about 1 kg and in the long term, the average difference was less than 1 kg.

People lost weight on both diets in some trials. The amount of weight lost on average varied greatly with both diets across the trials from less than 1 kg in some trials and up to about 12 kg in others in the short term and long term.

Similarly, low-carbohydrate weight-reducing diets probably result in little to no difference in diastolic blood pressure, glycosylated haemoglobin (HbA1c) and LDL cholesterol (‘unhealthy’ cholesterol) for up to two years.

The authors could not draw any conclusions about side effects reported by participants because very few trials reported these.

What are the limitations of the evidence?
The authors are moderately confident in the evidence. Confidence was lowered mainly because of concerns about how some the trials were conducted, which included that many trials did not report all their results. Further research may change these results.

How up to date is this evidence?
The evidence is up-to-date to June 2021.

What gaps did the authors identify?
They do not know if there are differences between the effects and safety of these diets beyond two years.

Since most of the people in the trials did not have heart disease or heart disease risks when they were recruited, the authors do not know if there are differences between the effects and safety of these diets in people with heart disease or risk factors, such as conditions that cause abnormal levels of fats in the blood.

What important related questions were not addressed in this review?
The author team did not compare type or quality of carbohydrates, fats or proteins between the diets. They also did not examine differences in costs between the diets.

Friday, January 28, 2022

What is an infodemic and how can we prevent it?: a Lifeology and Cochrane collaboration

Fri, 01/21/2022 - 16:22

In this free Lifeology course, learn what an infodemic is and what you can do to slow and prevent the spread of misinformation. 

Lifeology’s tagline is ‘The place where science and art converge’. They offer a platform that brings together scientists, artists, and storytellers to help people better understand and engage with science and health information and research. One of the main ways they meet their objectives is through beautifully illustrated, science-backed, bite-sized ‘flashcard’ courses about science and health-related topics aimed at the general public and students.

Image from the Lifeology's 'What is an infodemic and how can we prevent it?' course

For World Evidence-Based Healthcare (EBHC) Day, with the 2021 campaign theme of  'the role of evidence in an infodemic', they collaborated with Cochrane to create a free course. The 41 slides walk the user through the  story of Ronald who has been misguided by misinformation and teaches what an infodemic is and how to slow the spread of misinformation.

Image from the Lifeology's 'What is an infodemic and how can we prevent it?' course

Paige Jarreau, co-founder of Lifeology, said "At Lifeology, we believe that science communication in any format, including our flashcard courses, is far better when it is the product of collaboration between scientists and professional creatives like storytellers and artists. We were pleased to be able to work closely with people from Cochrane to create this course on infodemics. We've produced a beautifully illustrated free course that is practical in its tips to combat misinformation and accessible through its plain language, empathetic storytelling and relatable imagery  - it's also available in English, Malay, and Spanish !"

Image from the Lifeology's 'What is an infodemic and how can we prevent it?' course

Jordan Collver, the illustrator of the Lifeology course, said "This was an exciting project to work on. We had some fun with metaphors and with well known memes in this course while keeping the story empathic and relatable in a global context.'

  • View the Lifeology course 'what is an infodemic and how we can prevent it?' in English, Malay, or Spanish

Learn more about Lifeology: 

Friday, January 21, 2022

What's the accuracy of crowdsourcing the screening of search results? Help Cochrane find out!

Fri, 01/14/2022 - 10:01

Cochrane Crowd is a citizen science platform  where a global community of volunteers help to classify the research needed to support informed decision-making about healthcare. Cochrane Crowd volunteers review descriptions of research studies to identify and classify clinical trials.

 A new task has just gone live on Cochrane Crowd. It is a citation screening task that we are doing in partnership with The Healthcare Improvement Studies Institute (THIS Institute).

It forms a part of a methodological study that aims to assess the accuracy of crowdsourcing the screening of search results. Unlike some of the previous studies we’ve done, this one is a little bit different. Instead of asking you to assess a record for possible relevance, we want you to assess it for irrelevance! Our hypothesis is that a crowd can still make a big difference in weeding out the obviously irrelevant records, and that by framing the task in this way, we will reduce the chances of possibly relevant records being rejected.

Are you up for joining this task? If so, head to crowd.cochrane.org and log in. On your tasks page you should see a task called: Training for healthcare professionals in electronic fetal monitoring using cardiotocograph.



We are going to run this study as a randomised study. When you click on the training module, you will be randomised to one of three tasks. Each of the three tasks will look exactly the same. The difference between the three tasks is the agreement algorithm in the background. This algorithm provides a ‘final’ classification on a record based on a certain number and order of individual classifications made by contributors. We are testing three different agreement algorithms as part of this methodological study.

There is of course a training module. It should only take around 10-15 minutes to complete. Once done you will be able to screen some ‘real’ records. Do as many as you like. If you manage to do 250 or more, you will get named acknowledgement in any write-ups of this methods study and be able to download a certificate.


As always, this kind of work would not be possible without the help of this fantastic community. If you are able to take part, then thank you very much indeed from the teams at THIS Institute and Cochrane Crowd.

If you have any questions, please don’t hesitate to get in touch with me: anna.noel-storr@rdm.ox.ac.uk

With best wishes to all and happy citation screening!

Anna and Sarah

Friday, January 14, 2022

Cochrane seeks Chief Executive Officer

Thu, 01/13/2022 - 16:11

Location: UK based role with occasional global travel
Salary: £110-120,000 per annum
Contract type: Permanent
Date closing: 06/02/2022

Cochrane is a global independent community of more than 100,000 people who search for and summarize the best evidence from health and care research to help our beneficiaries make informed choices about health and care.  

Our members and supporters come from more than 220 countries worldwide including researchers, health professionals, patients, carers, and people passionate about improving health and care outcomes for everyone, everywhere.

Chief Executive
£110, 120,000 per annum
UK based role with occasional global travel

Cochrane’s work providing accessible, credible information to improve global health - has never been more important or relevant than it is today.

This Chief Executive role is an extraordinary opportunity for an inspirational, experienced and authentic leader, passionate about evidence and health care, to join Cochrane and work with a highly committed and engaged Board and talented staff team to lead the development of a new long-term strategy.

We are seeking someone with experience working in a multi-stakeholder environment, ideally in a global context, with exceptional interpersonal and communication skills with proven capacity to develop influential internal and external relationships.  Thoughtful, curious, and with a supportive leadership style; you will bring a strong track record of leading teams; fostering a high-performing culture; driving organisational change and growing income.  Critically, you will share our vision of a world of better health for all people where decisions about health and care are informed by high-quality evidence.

Cochrane is a global community and we value the diverse range of experience that this brings.  We strive to be an equal opportunities employer and welcome application from people from all races, religions, genders, sexual orientation, lived experience or ability.

  • For further information, the role and how to apply please download the full appointment brief here  
  • Closing Date: Sunday 6th February 2022
  • If you require this document in an alternative format, please contact executiveadmin@prospect-us.co.uk or call 020 7691 1920
Thursday, January 13, 2022 Category: Jobs

Research Integrity: making sure medical trials reported in the scientific literature are real

Thu, 01/13/2022 - 12:45

Senior Research Integrity Editor, Lisa Bero, discusses this subject in a recent Nature article.

Never has it been more important to foster trust in scientific evidence than in the ongoing coronavirus pandemic. Cochrane is committed to independence, transparency, and integrity in healthcare research. The Research Integrity Team works to support and strengthen this commitment through research, policy development and implementation, advocacy and community outreach.

Recently, Senior Research Integrity Editor, Lisa Bero, has written a World View in Nature on the topic of working together to tackle the issue of problematic studies – studies where there are serious concerns about the trustworthiness of the data or findings. In the article she explains the tools and resources Cochrane uses as described in its policy for ‘Managing potentially problematic studies’, to empower reviewers to act when they suspect an issue. 

Research Integrity Editor, Stephanie Boughton, says “It was great to highlight Cochrane’s leading work in this area. We are building upon Cochrane’s strong history of conducting meta-research to detect research integrity problems. I hope all systematic review authors take up Lisa’s call to action and use tools described in Cochrane’s policy for ‘Managing potential problematic studies’ when they suspect an issue.”

Wednesday, January 19, 2022

Cochrane UK seeks a Transition Support Project Manager

Mon, 01/10/2022 - 16:25

Specifications:  Part Time, 1 day per week
Location: UK based (remote)
Application Closing Date: 25 January 2022

Cochrane UK is seeking a dynamic, self-motivated Transition Support Project Manager to lead and manage a support service for UK-based Cochrane Review Groups (CRGs) and those who work with them during a period of transition to a new review production model. 

You will join a small and friendly team at Cochrane UK and will work closely with the UK-based CRGs, Cochrane’s Editorial and Methods Department (EMD) and Cochrane Support Service to develop and operate processes to minimize disruption during the transition period.   

You will have in-depth knowledge and understanding of the existing Cochrane publication model and editorial processes.  You will have experience of the processes involved in conducting and editing systematic reviews and submitting funding bids.  You will have excellent communication and project management skills with the ability to build effective stakeholder relationships.

The role will be for 1 day per week with the potential to increase if, and when,  the requirements of the project change over the next 12 months.   

This role can be arranged either as a secondment (with your employer’s permission) or with you working as a self-employed contractor. 

If you would like more information please contact Therese Docherty, Business & Programme Manager (therese.docherty@cochrane.nhs.uk) for the full job description and person specification.

Deadline for applications: 25 January 2022.

Monday, January 10, 2022 Category: Jobs

Cochrane seeks Project Manager

Mon, 01/10/2022 - 11:15

Specifications: Full Time
Salary:  £42,000 per annum
Location: UK based (remote)
Application Closing Date: 23 January 2022

Cochrane is a global independent network of health practitioners, researchers, patient advocates and others, responding to the challenge of making the vast amounts of evidence generated through research useful for informing decisions about health. We do this by identifying, appraising and synthesizing individual research findings to produce the best available evidence on what can work, what might harm and where more research is needed.

A Project Manager role has become available to support the Evidence Production and Methods Department (EPM), Publishing and Technology department (P&T), Cochrane Library Product Manager and other Central Executive Teams (CET) in delivering on high priority projects: to project manage the highest priority EPM, P&T and other Cochrane projects where appropriate.

  • For further information on the role and how to apply, please click here
  • The supporting statement should indicate why you are applying for the post, and how far you meet the requirements, using specific examples.
  • Note that we will assess applications as they are received, and therefore may fill the post before the deadline.
  • Deadline for applications: Sunday 23 January 2022 (12 midnight GMT).
Monday, January 10, 2022 Category: Jobs

Cochrane seeks Support Officer

Thu, 01/06/2022 - 15:18

Location: Flexible location (remote working) – contract type dependent on location.
Specifications: 1 Mar to 1 September 2022. Fixed-term employment contract if successful applicant based in UK, Germany or Denmark. Consultancy contract in other locations.
Hours: Full time 37.5 hours per week.
Salary: £30,000 per annum.
Application Closing Date: Sunday 23 January 2022 (Midnight GMT).

This role is an exciting opportunity to use your communication and problem-solving skills to make a difference in the field of healthcare research and publishing.  

Cochrane recently implemented Editorial Manager as the editorial and production system for Cochrane Reviews. This role has a significant focus on supporting authors, editors and peer reviewers in using Editorial Manager for submission and peer review; and our linked system Convey for managing Declarations of Interest. Applications are particularly welcomed from candidates with experience of using these or similar systems.

The Cochrane Support team provides technical and user support to Cochrane editorial teams and review authors; and handle enquiries from members of the public about Cochrane’s work. We pride ourselves on our timely and coordinated support service, covering a broad range of areas, with a focus on Cochrane review-writing software and editorial processing and publication.
The team works closely with Cochrane’s Central Editorial Service and other related departments, to ensure accurate, consistent responses to queries on Cochrane technology, policies and methods.

Cochrane is a global, independent network of health practitioners, researchers, patient advocates and others, responding to the challenge of making vast amounts of research evidence useful for informing decisions about health. We do this by synthesizing research findings to produce the best available evidence on what can work, what might harm and where more research is needed. Our work is recognised as the international gold standard for high quality, trusted information.

  • For further information on the role and how to apply, please click here  
  • The supporting statement should indicate why you are applying for the post, and how far you meet the requirements, using specific examples. Note that we will assess applications as they are received, and therefore may fill the post before the deadline
  • Deadline for applications: Sunday 23 January 2022 (12 midnight GMT)
  • Interviews to be held on: week beginning 31 January (times to be confirmed)
Thursday, January 6, 2022

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